BAI1 associated protein 2 isoform 3 peptide (509-520) (ab19041)

Product Name 

BAI1 associated protein 2 isoform 3 peptide (509-520)

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide: C-SMSSADVEVARF, corresponding to amino acids 509-520 of Human BAI1 associated protein 2 isoform 3.
BLAST 'C-SMSSADVEVARF' with or

Research areas 

Neuroscience >> Cell Type Marker >> Neuron marker >> Growth Cone

Relevance 

BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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