Anti-Pinkbar antibody (ab224323)
Key features and details
- Rabbit polyclonal to Pinkbar
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Pinkbar antibody
See all Pinkbar primary antibodies -
Description
Rabbit polyclonal to Pinkbar -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human Pinkbar aa 350-500.
Database link: Q6UXY1 -
Positive control
- IHC-P: Human small intestine tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab224323 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
May function as an adapter protein. -
Sequence similarities
Contains 1 IMD (IRSp53/MIM homology) domain.
Contains 1 SH3 domain. -
Domain
The IMD domain is predicted to have a helical structure. It may induce actin bundling and filopodia formation. - Information by UniProt
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Database links
- Entrez Gene: 80115 Human
- SwissProt: Q6UXY1 Human
- Unigene: 474822 Human
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Alternative names
- BAI1-associated protein 2-like 2 antibody
- BAI1-associated protein 2-like protein 2 antibody
- baiap2l2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab224323 has been referenced in 3 publications.
- Halford J et al. Ca2+ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips. Mol Biol Cell 33:br6 (2022). PubMed: 35044843
- Carlton AJ et al. Loss of Baiap2l2 destabilizes the transducing stereocilia of cochlear hair cells and leads to deafness. J Physiol 599:1173-1198 (2021). PubMed: 33151556
- Guo H et al. BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway. J Bone Oncol 31:100393 (2021). PubMed: 34786330