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Products:Signal Transduction >> Growth Factors/Hormones >> TGF
Overview
Product name
Anti-BAMBI antibody
Description
Mouse monoclonal to BAMBI
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-261 of Human BAMBI
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Stem Cells >> Signaling Pathways >> TGF beta >> Surface Molecules
Signal Transduction >> Growth Factors/Hormones >> TGF
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Western blot - BAMBI antibody (ab57043)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57043 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Negatively regulates TGF-beta signaling.
Tissue specificity
High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested.
Sequence similarities
Belongs to the BAMBI family.
Developmental stage
Expression in poorly metastatic human melanoma cell lines; no expression in highly metastatic human melanoma cell lines.
Cellular localization
Membrane.
Target information above from: UniProt accessionQ13145
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- BAMBI antibody
- BAMBI_HUMAN antibody
- BMP and activin membrane bound inhibitor homolog antibody
see all
Database links
- Entrez Gene: 25805 Human
- SwissProt: Q13145 Human
- Unigene: 533336 Human
Anti-BAMBI antibody images:
Western blot - BAMBI antibody (ab57043)
BAMBI antibody (ab57043) at 1ug/lane + K-562 cell lysate at 25ug/lane.
References for Anti-BAMBI antibody (ab57043)
This product has been referenced in:
- Wanninger Jet al. Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes. FEBS Lett 585:1338-44 (2011). WB; Human.Read more (PubMed: 21496456) »
See 1 publication for this product
Publishing research using ab57043? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"