Overview

  • Product nameAnti-BDNF antibody
    See all BDNF primary antibodies
  • Description
    Chicken polyclonal to BDNF
  • Tested applicationsELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Two peptides from human BDNF were mixed and used as immunogens. Both peptides are highly conserved among human and mouse sequences.

Properties

Applications

Our Abpromise guarantee covers the use of ab28952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/500 - 1/2000.

Target

  • FunctionDuring development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
  • Tissue specificityBrain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta.
  • Involvement in diseaseCongenital central hypoventilation syndrome
  • Sequence similaritiesBelongs to the NGF-beta family.
  • Post-translational
    modifications
    The propeptide is N-glycosylated and glycosulfated.
    Converted into mature BDNF by plasmin (PLG).
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Abrineurin antibody
    • BDNF antibody
    • BDNF antibody
    • BDNF_HUMAN antibody
    • Brain Derived Neurotrophic Factor antibody
    • Brain-derived neurotrophic factor antibody
    • MGC34632 antibody
    • Neurotrophin antibody
    see all

References for Anti-BDNF antibody (ab28952)

ab28952 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. Having reviewed the products in our catalogue I would suggest rabbit polyclonal Anti-BDNF ab46176 and Chicken polyclonal Anti-BDNF ab28952 may be suitable for your application. They have not, as far as we know, been used in...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"