Anti-BICD2 antibody (ab73286)
Key features and details
- Rabbit polyclonal to BICD2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-BICD2 antibody
See all BICD2 primary antibodies -
Description
Rabbit polyclonal to BICD2 -
Host species
Rabbit -
Specificity
this antibody does not cross react with BICD1. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to a 13 amino acid peptide from near the carboxy terminus of human BICD2.
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Positive control
- A549 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab73286 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa).
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Notes |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa). |
Target
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Function
May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the BicD family. -
Domain
The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2. -
Post-translational
modificationsPhosphorylated by NEK9 in vitro. -
Cellular localization
Golgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology. - Information by UniProt
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Database links
- Entrez Gene: 23299 Human
- Omim: 609797 Human
- SwissProt: Q8TD16 Human
- Unigene: 436939 Human
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Alternative names
- bA526D8.1 antibody
- Bic D 2 antibody
- Bic-D 2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab73286 has been referenced in 1 publication.
- Turgay Y et al. SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol 204:1099-109 (2014). PubMed: 24662567