![Western blot - BLMH antibody [2079C4a] (ab50988) image](#ab50988wb.jpg)
Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Overview
Product name
Anti-BLMH antibody [2079C4a]
See all BLMH products (3) ...
Description
Mouse monoclonal [2079C4a] to BLMH
Tested applications
Dot Blot, WBmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment (Human)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
Filtered through a 0.22 µm membrane.
Clonality
Monoclonal
Clone number
2079C4a
Isotype
IgG2b
Research areas
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Other proteases
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
-
Western blot - BLMH antibody [2079C4a] (ab50988)
![Western blot - BLMH antibody [2079C4a] (ab50988) image](/ps/datasheet/Images/50/ab50988/ab50988wb.jpg)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab50988 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Dot: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 53 kDa.
Target
Relevance
BLMH is a member of the peptidase C1 family and exists as a homohexamer. While its normal physiological function is not known, it protects normal and malignant cells from the glycopeptide antitumor drug BLM. It inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine and also shows general aminopeptidase activity. The specificity varies but amino acid arylamides of Met, Leu and Ala are preferred.
Cellular localization
Cytoplasmic
Alternative names
- BH antibody
- bleomycin hydrolase antibody
- BLM hydrolase antibody
see all
Database links
- Entrez Gene: 642 Human
- Omim: 602403 Human
- SwissProt: Q13867 Human
- Unigene: 371914 Human
Anti-BLMH antibody [2079C4a] images:
Western blot - BLMH antibody [2079C4a] (ab50988)
Anti-BLMH antibody [2079C4a] (ab50988) at 1/100 dilution + Recombinant fragment
Predicted band size : 53 kDa
Observed band size : 33 kDa (why is the actual band size different from the predicted?)
References for Anti-BLMH antibody [2079C4a] (ab50988)
ab50988 has not yet been referenced specifically in any publications.
Publishing research using ab50988? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"