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Anti-BMP11 antibody - Aminoterminal end (ab71347)

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Overview

  • Product nameAnti-BMP11 antibody - Aminoterminal endSee all BMP11 primary antibodies ...
  • Description
    Rabbit polyclonal to BMP11 - Aminoterminal end
  • Tested applicationsELISA, IHC-P, WB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) conjugated to KLH

  • Positive controlWB: 293 cell lysate IHC-P: human colon carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab71347 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA ELISA: 1/1000.
IHC-P IHC-P: 1/10 - 1/50.
WB WB: 1/50 - 1/100. Detects a band of approximately 55 kDa (predicted molecular weight: 45 kDa).

Target

  • RelevanceBMP11 is a member of the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. BMP11 is a secreted signal that acts globally to specify positional identity along the anterior/ posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
  • Cellular localizationSecreted
  • Database links
    • Alternative names
        BMP 11 antibodyBMP11 antibodyBone morphogenetic protein 11 antibody
        GDF 11 antibodyGrowth differentiation factor 11 antibody
      see all

    Anti-BMP11 antibody - Aminoterminal end images

    • Western blot - BMP11 antibody - Aminoterminal end (ab71347)
      Western blot - BMP11 antibody - Aminoterminal end (ab71347)
      All lanes : Anti-BMP11 antibody - Aminoterminal end (ab71347) at 1/50 dilution

      Lane 1 : 293 cell lysate, non transfected
      Lane 2 : 293 cell lysate, transiently transfected with the BMP11 gene

      Lysates/proteins at 2 µg per lane.


      Predicted band size : 45 kDa
      Observed band size : 55 kDa (why is the actual band size different from the predicted?)
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - BMP11 antibody - Aminoterminal end (ab71347)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - BMP11 antibody - Aminoterminal end (ab71347)
      ab71347, at a dilution of 1/10, staining BMP11 in formalin fixed, paraffin embedded human colon carcinoma tissue sections by Immunohistochemistry.

    References for Anti-BMP11 antibody - Aminoterminal end (ab71347)

    ab71347 has not yet been referenced specifically in any publications.

    Publishing research using ab71347 ? Please let us know so that we can cite the reference in this datasheet

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    will do WB with human and mouse protein (mature protein)
    ab124721: immunogen range (located in mature protein or outside)?
    other 3 Abs can be used to detect mature protein?

    Thank you for contacting us.

    I have gathered the following information:


    ab124721: The immunogen range is located within the mature human protein (aa 299 - 407).


    ab56645:immunogne is a recombinant fragment: ESRCCRY...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"