Anti-BMP2 antibody (ab14933)
Key features and details
- Rabbit polyclonal to BMP2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-BMP2 antibody
See all BMP2 primary antibodies -
Description
Rabbit polyclonal to BMP2 -
Host species
Rabbit -
Specificity
ab14933 detects only the pro-form of the BMP2 -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
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Positive control
- WB: HeLa, THP, HepG2 and Huh7 cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 30% Glycerol, 0.75% BSA
The antibody is provided in antibody stabilization buffer containing phosphate buffer, pH 7.4, glycerol, stabilizing proteins and preservatives. The exact buffer contents are considered proprietary. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab14933 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (6) |
1/500 - 1/1000. Detects a band of approximately 45 kDa.
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 45 kDa. |
Target
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Function
Induces cartilage and bone formation. -
Tissue specificity
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 650 Human
- Omim: 112261 Human
- SwissProt: P12643 Human
- Unigene: 73853 Human
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Alternative names
- BDA2 antibody
- BMP-2 antibody
- BMP-2A antibody
see all
Images
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All lanes : Anti-BMP2 antibody (ab14933) at 1/500 dilution
Lane 1 : HeLa cells
Lane 2 : THP cells
Lane 3 : HepG2 cells
Lane 4 : Huh7 cellsCell extracts were made in protein extraction buffer (Solobuffer) with protease inhibitor cocktail.
Total 40-50ug of protein was applied in each lane on a 10% SDSPAGE,
The gel was transferred on to Immobilon F and blotted with ab14933.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (161)
ab14933 has been referenced in 161 publications.
- Wang Y et al. SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling. Cardiovasc Res 118:913-928 (2022). PubMed: 33757126
- Fu X et al. Molecular mechanism of albumin in suppressing invasion and metastasis of hepatocellular carcinoma. Liver Int 42:696-709 (2022). PubMed: 34854209
- Li C et al. The osteoprotective role of USP26 in coordinating bone formation and resorption. Cell Death Differ 29:1123-1136 (2022). PubMed: 35091692
- Skauli N et al. Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes. Front Cell Neurosci 16:878154 (2022). PubMed: 35518645
- Lektemur Alpan A et al. Evaluation of the Effects of Favipiravir Combined with Vitamin C on Alveolar Bone in Rats. J Evol Biochem Physiol 58:430-440 (2022). PubMed: 35599639