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BMP2 protein (ab50099)

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Overview

Product name

BMP2 protein
See all BMP2 products (4) ...

Protein description

Recombinant Human BMP2. A 26 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains.

Expression host

E. coli

Properties

Purity

>95% by SDS-PAGE

Purification notes

Greater than 98% by SDS-PAGE.

Form

Lyophilised:
Centrifuge the vial prior to opening. Reconstitute in water containing BSA (50ug of BSA per 1ug of protein) to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Concentration

Concentration information loading...

Sequence notes

MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

Research areas

Stem Cells >> Stem Cell Cytokines >> Recombinant Human
Cancer >> Growth factors >> TGF
Stem Cells >> Neural Stem Cells >> Extracellular
Stem Cells >> Signaling Pathways >> TGF beta >> Secreted
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> Structures >> Bone
Signal Transduction >> Growth Factors/Hormones >> TGF

Applications

Show applications key

Our Abpromise guarantee covers the use of ab50099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    Cellular activation

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    CellAct: Use at an assay dependent dilution. (The ED50 for inducing alkaline phosphatase production by ATDC-5 cells is < 1µg/ml. )

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    SDS-PAGE

     SDS-PAGE: Use at an ass...Read more →

    SDS-PAGE: Use at an assay dependent dilution.

Protein info

Function

Induces cartilage and bone formation.

Tissue specificity

Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

Sequence similarities

Belongs to the TGF-beta family.

Cellular localization

Secreted.

Target information above from: UniProt accessionP12643 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for BMP2 protein (ab50099)

ab50099 has not yet been referenced specifically in any publications.

Publishing research using ab50099? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"