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Product Name
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BMP3 antibody
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See all BMP3 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to BMP3
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Immunogen
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Synthetic peptide: CSIVRAVGVVPG conjugated to KLH, corresponding to amino acids 59-69 of the native molecule of BMP3.
BLAST 'CSIVRAVGVVPG' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat, Cow, Xl
(Due to sequence homology)
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Specificity
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ab53886 is expected to react with BMP3 and BMP3b (GDF-10) by sequence homology.
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 53 kDa.
ab53886 is reactive in blotting with Bovine BMP3 giving a strong band under non-reducing conditions at around 16-18 kD. This band however is not blocked by the peptide.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> Structures >> Bone
Signal Transduction >> Growth Factors/Hormones >> TGF
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Relevance
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BMPs (bone morphogenetic proteins) belong to the Transforming Growth Factor beta (TGF beta) superfamily of structurally related signaling proteins. Proteins of the TGF beta superfamily are disulfide linked dimmers composed of two 12-15 kDa polypeptide chains. All the proteins in this superfamily are involved in embryonic development and the maintenance of adult tissue. BMPs initiate, promote and regulate bone development, growth, remodeling and repair. In vivo studies have shown that BMP3 can independently induce cartilage formation.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Ammonium Sulphate Precipitation
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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4.200 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BMP3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to BMP3
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BMP3 antibody - more information
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Customer reviews (feedback) regarding BMP3 antibody |
Customer FAQs regarding BMP3 antibody |
Protocols for BMP3 antibody |
Price and availability of products related to BMP3 antibody |
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BMP3 antibody - related products:
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BMP3 antibody - other tools:
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Contact Abcam with a Technical Enquiry about BMP3 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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