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Products:Signal Transduction >> Growth Factors/Hormones >> TGF
Overview
Product name
Anti-BMP3 antibody
See all BMP3 products (4) ...
Description
Rabbit polyclonal to BMP3
Specificity
ab71500 detects the ~55 kDa full length and the ~16 kDa cleaved fragment of BMP3.
Tested applications
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
Synthetic peptide surrounding amino acid 369 of mouse BMP3.
Positive control
3T3 cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 30% Glycerol, 0.5% BSA, PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> Structures >> Bone
Signal Transduction >> Growth Factors/Hormones >> TGF
-
Western blot - BMP3 antibody (ab71500)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab71500 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 0.5 - 4 µg/ml. Detects bands of approximately 16 and 55 kDa (predicted molecular weight: 53 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
Tissue specificity
Expressed in adult and fetal cartilage.
Sequence similarities
Belongs to the TGF-beta family.
Cellular localization
Secreted.
Target information above from: UniProt accessionP12645
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- BMP-3 antibody
- BMP-3A antibody
- bmp3 antibody
see all
Database links
- Entrez Gene: 651 Human
- Entrez Gene: 110075 Mouse
- Entrez Gene: 25667 Rat
- Omim: 112263 Human
- SwissProt: P12645 Human
- SwissProt: Q8BHE5 Mouse
- SwissProt: P49002 Rat
- Unigene: 387411 Human
see all
Anti-BMP3 antibody images:
Western blot - BMP3 antibody (ab71500)
Anti-BMP3 antibody (ab71500) at 0.5 µg/ml + 3T3 cell lysate
Predicted band size : 53 kDa
Observed band size : 55 kDa (why is the actual band size different from the predicted?)
Additional bands at : 16 kDa (possible cleavage fragment).
References for Anti-BMP3 antibody (ab71500)
ab71500 has not yet been referenced specifically in any publications.
Publishing research using ab71500? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"