BMP4 antibody [3H2] (ab81194)

Product Name 

BMP4 antibody [3H2]

Product type 

Primary antibodies

Description 

Mouse monoclonal [3H2] to BMP4

Immunogen 

Recombinant Human BMP4 Protein

Reacts with 
(species key)

Hu

Tested applications 
(see key)

IHC-P, WB

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
IHC-P: 1/25 - 1/50.
WB: 1/25 - 1/50. Predicted molecular weight: 47 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Saos-2 cell lysate

Cellular localization 

Secreted, extracellular matrix.

Research areas 

Developmental Biology >> Organogenesis >> Excretory system development >> Kidney development
Developmental Biology >> Organogenesis >> Nervous system development
Developmental Biology >> Organogenesis >> Gut development >> Gut specification
Cancer >> Growth factors >> TGF
Stem Cells >> Signaling Pathways >> TGF beta >> Secreted
Signal Transduction >> Growth Factors/Hormones >> TGF
Cardiovascular >> Angiogenesis >> Growth Factors >> TGF

Relevance 

BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Database links 

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

3H2

Isotype 

IgG2b

Purity 

Tissue culture supernatant

Storage buffer 

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Customer reviews (feedback) regarding BMP4 antibody [3H2]

Customer FAQs regarding BMP4 antibody [3H2]

Protocols for BMP4 antibody [3H2]

Price and availability of products related to BMP4 antibody [3H2]

BMP4 antibody [3H2] - related products: