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Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - BMP4 antibody (ab31165)
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Product Name
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BMP4 antibody
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See all BMP4 antibodies (7)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to BMP4
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Immunogen
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Recombinant full length protein: human BMP4.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: 1/50 for 30 min at RT. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol, by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min..
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Bone marrow
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Cellular localization
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Secreted, extracellular matrix.
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Research areas
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Developmental Biology >> Organogenesis >> Excretory system development >> Kidney development
Developmental Biology >> Organogenesis >> Nervous system development
Developmental Biology >> Organogenesis >> Gut development >> Gut specification
Cancer >> Growth factors >> TGF
Stem Cells >> Signaling Pathways >> TGF beta >> Secreted
Signal Transduction >> Growth Factors/Hormones >> TGF
Cardiovascular >> Angiogenesis >> Growth Factors >> TGF
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Relevance
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BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 10mM PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.200 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BMP4 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for BMP4 antibody images, references, products related to ab31165 and other tools.
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BMP4 antibody images:
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 Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - BMP4 antibody (ab31165)
Human bone marrow stained with anti-BMP4 (ab31165, diluted 1:50).
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Search PubMed (MEDLINE) for references to BMP4
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BMP4 antibody - more information
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Customer reviews (feedback) regarding BMP4 antibody |
Customer FAQs regarding BMP4 antibody |
Protocols for BMP4 antibody |
Price and availability of products related to BMP4 antibody |
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BMP4 antibody - related products:
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BMP4 antibody - other tools:
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Contact Abcam with a Technical Enquiry about BMP4 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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