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Overview

  • Product nameBMP7 protein (Human)See all BMP7 proteins and peptides ...
  • Protein descriptionRecombinant full length Human BMP7 (aa 293-431) expressed in modified human 293 cells (Swiss-Prot P18075).
  • Expression hostHEK 293 cells

    • Properties

  • Purity> 95 % by SDS-PAGE
  • FormLyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial. Following reconstitution short-term storage at 4°C is recommended, with longer-term storage in aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.
  • Storage instructionsShipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 10% Trehalose, 1% Human serum albumin
  • Concentration information loading...
  • Sequence notesTheoretical sequence: STGSKQRSQNRSKTPKNQEALRMANVAEN SSSDQRQACKKHELYVSFRDLGWQDWIIAP EGYAAYYC EGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPT QLNAISVLYFDDSS NVILKKYRNMVVRACGCH
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab83921 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent concentration. Ab83921 can be used as a WB positive control in conjunction with ab84684.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution. Migrates as a broad band between 15 and 16 kDa due to post-translation modifications, in particular glycosylation.
  • Application notesThis peptide can be used with studies using ab35086,ab84684 and ab113903.

    • Protein info

    • Alternative names
        BMP 7BMP-7Bmp7
        BMP7_HUMANBone morphogenetic protein 7Bone morphogenic protein 7Eptotermin alfaOP 1OP-1OP1Osteogenic protein 1
      see all
  • FunctionInduces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
  • Tissue specificityExpressed in the kidney and bladder. Lower levels seen in the brain.
  • Sequence similaritiesBelongs to the TGF-beta family.
  • Developmental stageExpressed in the developing eye, brain and ear during embryogenesis.
  • Post-translational
    modifications    Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P18075 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    BMP7 protein (Human) images

    • Western blot - Anti-BMP7 antibody (ab84684)
      Western blot - Anti-BMP7 antibody (ab84684)
      Anti-BMP7 antibody (ab84684) at 1/1 dilution + BMP7 protein (Human) (ab83921) at 0.1 µg

      Secondary
      Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed (ab97080) at 1/5000 dilution
      developed using the ECL technique

      Performed under reducing conditions.

      Exposure time : 1 minute

    References for BMP7 protein (Human) (ab83921)

    ab83921 has not yet been referenced specifically in any publications.

    Publishing research using ab83921 ? Please let us know so that we can cite the reference in this datasheet

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