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Overview

  • Product nameAnti-BNIP3 antibody [ANa40]See all BNIP3 primary antibodies ...
  • Description
    Mouse monoclonal [ANa40] to BNIP3
  • Specificityab88729 recognizes an epitope of residues 112-124 from human BNIP3.
  • Tested applicationsELISA, ICC, IP, WB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to N terminal amino acids 1-163 of Human BNIP3

Properties

Applications

Our Abpromise guarantee covers the use of ab88729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA
ICC
IP
WB
  • Application notesELISA: Use at an assay dependent dilution.
    ICC: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.
    WB: Use at a concentration of 2 - 4 µg/ml. Predicted molecular weight: 22 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionApoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
    • Sequence similaritiesBelongs to the NIP3 family.
    • Cellular localizationMitochondrion. Mitochondrion membrane. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria.

      • Target information above from: UniProt accession Q12983 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          BCL2 Adenovirus E1B 19kDa Interacting Protein 3 antibodyBCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibodyBCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody
          BNIP 3 antibodyBNIP3 antibodyBNIP3_HUMAN antibodyNIP 3 antibodyNIP3 antibody
        see all

      References for Anti-BNIP3 antibody [ANa40] (ab88729)

      This product has been referenced in:
      • Chaanine AH  et al. JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure. Cell Death Dis 3:265 (2012). WB ; Rat . Read more (PubMed: 22297293) »

      See 1 Publication for this product

      Publishing research using ab88729 ? Please let us know so that we can cite the reference in this datasheet

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