Overview

  • Product name
    Anti-BNIP3 antibody [ANa40]
    See all BNIP3 primary antibodies
  • Description
    Mouse monoclonal [ANa40] to BNIP3
  • Specificity
    ab88729 recognizes an epitope of residues 112-124 from human BNIP3.
  • Tested applications
    Suitable for: ELISA, ICC, IP, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to N terminal amino acids 1-163 of Human BNIP3

Properties

Applications

Our Abpromise guarantee covers the use of ab88729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
ICC
IP
WB
  • Application notes
    ELISA: Use at an assay dependent dilution.
    ICC: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.
    WB: Use at a concentration of 2 - 4 µg/ml. Predicted molecular weight: 22 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
    • Sequence similarities
      Belongs to the NIP3 family.
    • Cellular localization
      Mitochondrion. Mitochondrion membrane. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria.
    • Information by UniProt
    • Database links
    • Alternative names
      • BCL2 Adenovirus E1B 19kDa Interacting Protein 3 antibody
      • BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody
      • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody
      • BNIP 3 antibody
      • BNIP3 antibody
      • BNIP3_HUMAN antibody
      • NIP 3 antibody
      • NIP3 antibody
      see all

    References

    This product has been referenced in:
    • Chaanine AH  et al. JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure. Cell Death Dis 3:265 (2012). WB ; Rat . Read more (PubMed: 22297293) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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