Overview
- Product nameAnti-BNIP3L antibodySee all BNIP3L primary antibodies ...
- DescriptionRabbit polyclonal to BNIP3L
- SpecificitySpecific for BNIP3L
- Tested applicationsWB, IHC-P, IHC-Fr more details
- Species reactivityReacts with: Mouse, Rat, Human
- Immunogen
Synthetic peptide from an internal region of rat BNIP3L conjugated to an immunogenic carrier protein. (The antigen is homologous in human and mouse).
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50%, aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: 1X PBS - PurityWhole antiserum
- Clonality Polyclonal
- IsotypeIgG
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Research Areas
Applications
Our Abpromise guarantee covers the use of ab83808 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/300 - 1/2000. Predicted molecular weight: 24 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein. |
| IHC-P | IHC-P: 1/300 - 1/2000. |
| IHC-Fr | IHC-Fr: 1/300 - 1/2000. |
Target
- FunctionInduces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor suppressor. Inhibits apoptosis induced by BNIP3.
- Sequence similaritiesBelongs to the NIP3 family.
- Post-translational
modificationsUndergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin. - Cellular localizationNucleus envelope. Endoplasmic reticulum. Mitochondrion. Membrane.
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Database links
- Entrez Gene: 665 Human
- Entrez Gene: 12177 Mouse
- Entrez Gene: 140923 Rat
- Omim: 605368 Human
- SwissProt: O60238 Human
- SwissProt: Q9Z2F7 Mouse
- Unigene: 131226 Human
- Unigene: 29820 Mouse
- Unigene: 347081 Mouse
- Unigene: 827 Rat
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Target information above from: UniProt accession
O60238
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Adenovirus E1B19k binding protein B5 antibodyAdenovirus E1B19K-binding protein B5 antibodyBCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody
- BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibodyBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibodyBCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibodyBCL2/adenovirus E1B 19kDa interacting protein 3 like antibodyBNI3L_HUMAN antibodyBNIP3a antibodyBNIP3H antibodyBNIP3L antibodyBNIP3L protein antibodyNIP3 like protein X antibodyNIP3-like protein X antibodyNIP3L antibodyNIX antibody
see all
References for Anti-BNIP3L antibody (ab83808)
ab83808 has not yet been referenced specifically in any publications.
