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Overview

  • Product nameAnti-BNIP3L antibody, predilutedSee all BNIP3L primary antibodies ...
  • Description
    Rabbit polyclonal to BNIP3L, prediluted
  • Tested applicationsIHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to internal region of human BNIP3L protein

  • Positive controlK562 cells. Breast carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab53208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
  • Application notesIHC-P: Ready-to-use for 30 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionInduces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor suppressor. Inhibits apoptosis induced by BNIP3.
    • Sequence similaritiesBelongs to the NIP3 family.
    • Post-translational
      modifications      Undergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin.
    • Cellular localizationNucleus envelope. Endoplasmic reticulum. Mitochondrion. Membrane.

      • Target information above from: UniProt accession O60238 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          Adenovirus E1B19k binding protein B5 antibodyAdenovirus E1B19K-binding protein B5 antibodyBCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody
          BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibodyBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibodyBCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibodyBCL2/adenovirus E1B 19kDa interacting protein 3 like antibodyBNI3L_HUMAN antibodyBNIP3a antibodyBNIP3H antibodyBNIP3L antibodyBNIP3L protein antibodyNIP3 like protein X antibodyNIP3-like protein X antibodyNIP3L antibodyNIX antibody
        see all

      References for Anti-BNIP3L antibody, prediluted (ab53208)

      ab53208 has not yet been referenced specifically in any publications.

      Publishing research using ab53208 ? Please let us know so that we can cite the reference in this datasheet

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