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Overview

  • Product nameAnti-BRUNOL5 antibodySee all BRUNOL5 primary antibodies ...
  • Description
    Rabbit polyclonal to BRUNOL5
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 359-408 (AFSGVQQYTA MYPTAAITPI AHSVPQPPPL LQQQQREGPE GCNLFIYHLP) of Human BRUNOL5 (NP_068757)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive controlA549 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab102122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
  • Tissue specificityExpressed in brain.
  • Sequence similaritiesBelongs to the CELF/BRUNOL family.
    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localizationNucleus. Cytoplasm.

    • Target information above from: UniProt accession Q8N6W0 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Bruno like 5, RNA binding protein (Drosophila) antibodyBruno like protein 5 antibodyBruno-like protein 5 antibody
        BRUNOL 5 antibodyCELF 5 antibodyCELF-5 antibodyCELF5 antibodyCELF5_HUMAN antibodyCUG BP and ETR 3 like factor 5 antibodyCUG-BP- and ETR-3-like factor 5 antibodyCUGBP Elav-like family member 5 antibodyCUGBP, Elav-like family member 5 antibodyRNA binding protein BRUNOL5 antibodyRNA-binding protein BRUNOL-5 antibody
      see all

    Anti-BRUNOL5 antibody images

    • Western blot - Anti-BRUNOL5 antibody (ab102122)
      Western blot - Anti-BRUNOL5 antibody (ab102122)
      Anti-BRUNOL5 antibody (ab102122) at 1 µg/ml + A549 cell lysate at 10 µg

      Predicted band size : 52 kDa

    References for Anti-BRUNOL5 antibody (ab102122)

    ab102122 has not yet been referenced specifically in any publications.

    Publishing research using ab102122 ? Please let us know so that we can cite the reference in this datasheet

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