Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab77343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA
WB
  • Application notesELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/1000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 52 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
    • Tissue specificityExpressed in brain.
    • Sequence similaritiesBelongs to the CELF/BRUNOL family.
      Contains 3 RRM (RNA recognition motif) domains.
    • Cellular localizationNucleus. Cytoplasm.
    • Target information above from: UniProt accession Q8N6W0 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • Alternative names
      • Bruno like 5, RNA binding protein (Drosophila) antibody
      • Bruno like protein 5 antibody
      • Bruno-like protein 5 antibody
      • BRUNOL 5 antibody
      • CELF 5 antibody
      • CELF-5 antibody
      • CELF5 antibody
      • CELF5_HUMAN antibody
      • CUG BP and ETR 3 like factor 5 antibody
      • CUG-BP- and ETR-3-like factor 5 antibody
      • CUGBP Elav-like family member 5 antibody
      • CUGBP, Elav-like family member 5 antibody
      • RNA binding protein BRUNOL5 antibody
      • RNA-binding protein BRUNOL-5 antibody
      see all

    Anti-BRUNOL5 antibody images

    References for Anti-BRUNOL5 antibody (ab77343)

    ab77343 has not yet been referenced specifically in any publications.

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