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Products:Cell Biology >> Apoptosis >> Intracellular >> Bcl2 Family
Overview
Product name
Anti-Bag5 antibody
See all Bag5 products (6) ...
Description
Mouse monoclonal to Bag5
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-448 of Human Bag5
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Cancer >> Invasion/microenvironment >> Apoptosis >> Bcl 2 family
Cell Biology >> Apoptosis >> Intracellular >> Bcl2 Family
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Western blot - Bag5 antibody (ab56738)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab56738 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
Sequence similarities
Contains 5 BAG domains.
Domain
The fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
Target information above from: UniProt accessionQ9UL15
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- BAG family molecular chaperone regulator 5 antibody
- BAG-5 antibody
- BAG5 antibody
see all
Database links
- Entrez Gene: 9529 Human
- Omim: 603885 Human
- SwissProt: Q9UL15 Human
- Unigene: 5443 Human
Anti-Bag5 antibody images:
Western blot - Bag5 antibody (ab56738)
Bag5 antibody (ab56738) at 1ug/lane + Jurkat cell lysate at 25ug/lane.
References for Anti-Bag5 antibody (ab56738)
This product has been referenced in:
- Gong C & Maquat LE lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature 470:284-8 (2011). WB; Human.Read more (PubMed: 21307942) »
See 1 publication for this product
Publishing research using ab56738? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"