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Products:Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Overview
Product name
Anti-BarX2 antibody [BAR X2 8A7/1]
See all BarX2 products (2) ...
Description
Mouse monoclonal [BAR X2 8A7/1] to BarX2
Tested applications
WB, IHC-P, IF, ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Fusion protein: MBP-tagged BarX2 (Human).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Primary antibody notes
BarX2 is a tumour suppressor gene that encodes for a transcription factor known to regulate transcription of cell adhesion molecules in the mouse.
Clonality
Monoclonal
Clone number
BAR X2 8A7/1
Myeloma
Sp2/0-Ag14
Isotype
IgG1
Light chain type
unknown
Applications
Show applications key
Our Abpromise guarantee covers the use of ab20128 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa.
IHC-P: 1/2Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
IF
IF: 1/500IF: 1/500
ELISA: Use at an assay dependent dilution.
Target
Function
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia.
Tissue specificity
Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta.
Sequence similarities
Belongs to the BAR homeobox family.
Contains 1 homeobox DNA-binding domain.
Post-translational
modifications
Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ9UMQ3
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- BarH like homeobox 2 antibody
- BarX 2 antibody
- BARX homeobox antibody
see all
Database links
- Entrez Gene: 8538 Human
- Omim: 604823 Human
- SwissProt: Q9UMQ3 Human
- Unigene: 167218 Human
- Unigene: 591944 Human
References for Anti-BarX2 antibody [BAR X2 8A7/1] (ab20128)
ab20128 has not yet been referenced specifically in any publications.
Publishing research using ab20128? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"