Bcl10 / CIPER/ CLAP / mE10 is expressed in many human and murine tissues. It contains a CARD (caspase recruiting domain) domain and is involved in activation of caspase9 to induce apoptosis. It is a cellular homolog of equine herpesvirus 2 E-10. It is known to induce activation of JNK, p38 and NF kappaB. Mutations in Bcl10 are observed in many B and T cell lymphomas implicating its role in pathogenesis of human cancer.
Bcl10 antibody (ab19884)
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Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
Form
Liquid
Concentration
0.500 mg/ml
Storage instructions
Store at +4°C.
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