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Western blot - Bcl3 antibody [Ham150-3.5] (ab15046)
![Western blot - Bcl3 antibody [Ham150-3.5] (ab15046)](/ps/datasheet/images/various.jpg)
(enlarge)
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Product Name
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Bcl3 antibody [Ham150-3.5]
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See all Bcl3 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Hamster monoclonal [Ham150-3.5] to Bcl3
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Immunogen
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Full length mouse Bcl3 protein.
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Reacts with
(species key)
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Hu, Ms
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Specificity
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Ab15046 recognises Bcl3 from transfected cells and shows no cross reactivity to other Bcl isoforms.
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 2 µg/ml. Detects a band of approximately 47 kDa (predicted molecular weight: 50 kDa).
Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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C57BI/6 human T cells and Bcl3 transgenic ms T cells.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> NFkB pathway Chromatin and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes Immunology >> Adaptive Immunity >> B Cells >> Non-CD
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Relevance
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This gene is a protooncogene candidate. It is identified by its translocation into the immunoglobulin alpha locus in some cases of B cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co activator that activates through its association with NFkappa B homodimers. The expression of this gene can be induced by NFkappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NFkappa B.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Hamster
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Clonality
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Monoclonal
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Clone number
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Ham150-3.5
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.05% Sodium Azide Constituents: 1mg/ml BSA Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Bcl3 antibody [Ham150-3.5] is on this datasheet. But please do contact us if you would like any reassurance! |
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Bcl3 antibody [Ham150-3.5] images:
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Western blot - Bcl3 antibody [Ham150-3.5] (ab15046)
Bcl3 antibody [Ham150-3.5] (ab15046) at 2 µg/ml
Predicted band size : 50 kDa
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Search PubMed (MEDLINE) for references to Bcl3
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Bcl3 antibody [Ham150-3.5] - more information
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Bcl3 antibody [Ham150-3.5] - other tools:
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"