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Western blot - Bcl3 antibody [Ham150-3.5] (ab15046)
Western blot - Bcl3 antibody [Ham150-3.5] (ab15046)
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Product Name 

Bcl3 antibody [Ham150-3.5]

 

See all Bcl3 antibodies (4)...

Product type 

Primary antibodies

Description 

Hamster monoclonal [Ham150-3.5] to Bcl3

Immunogen 

Full length mouse Bcl3 protein.

Reacts with 
(species key)

Hu, Ms

Specificity 

Ab15046 recognises Bcl3 from transfected cells and shows no cross reactivity to other Bcl isoforms.

Tested applications 
(see key)

ELISA, WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at a concentration of 2 µg/ml. Detects a band of approximately 47 kDa (predicted molecular weight: 50 kDa).

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

C57BI/6 human T cells and Bcl3 transgenic ms T cells.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> NFkB pathway
Chromatin and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes
Immunology >> Adaptive Immunity >> B Cells >> Non-CD

Relevance 

This gene is a protooncogene candidate. It is identified by its translocation into the immunoglobulin alpha locus in some cases of B cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co activator that activates through its association with NFkappa B homodimers. The expression of this gene can be induced by NFkappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NFkappa B.

 

Alternative names Bcl3 antibody [Ham150-3.5] (ab15046)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

602    (Human)
12051    (Mouse)

GeneCard

    

GC19P049943    (Human)

Omim

    

109560    (Human)

SwissProt

    

P20749    (Human)
Q9Z2F6    (Mouse)
Q3U300    (Mouse)

Unigene

    

31210    (Human)

Raised in 

Hamster

Clonality 

Monoclonal

Clone number 

Ham150-3.5

Isotype 

IgG

Purity 

Protein G purified

Storage buffer 

Preservative: 0.05% Sodium Azide
Constituents: 1mg/ml BSA

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Bcl3 antibody [Ham150-3.5] is on this datasheet. But please do contact us if you would like any reassurance!


 

Bcl3 antibody [Ham150-3.5] images:

Product image  Western blot - Bcl3 antibody [Ham150-3.5] (ab15046)

Western blot - Bcl3 antibody [Ham150-3.5] (ab15046)

Bcl3 antibody [Ham150-3.5] (ab15046) at 2 µg/ml

Predicted band size : 50 kDa

 
 

Search PubMed (MEDLINE) for references to Bcl3

 

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