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Product Name
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Bcl3 antibody
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See all Bcl3 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Bcl3
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Immunogen
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Synthetic peptide (Human) - mapping to the C terminus of Bcl 3.
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Reacts with
(species key)
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Hu, Ms, Rat
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Tested applications
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IHC-Fr, IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions IHC-Fr: Use at a concentration of 20 - 40 µg/ml. IP: Use at a concentration of 5 - 10 µg/ml. WB: Use at a concentration of 1 - 4 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 47 kDa).
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> NFkB pathway Chromatin and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes Immunology >> Adaptive Immunity >> B Cells >> Non-CD
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Relevance
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This gene is a protooncogene candidate. It is identified by its translocation into the immunoglobulin alpha locus in some cases of B cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co activator that activates through its association with NFkappa B homodimers. The expression of this gene can be induced by NFkappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NFkappa B.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.02% Thimerosal (merthiolate) Constituents: 50% Glycerol, 1.0% BSA, PBS, pH 7.2 Material safety datasheets (MSDS) for this product: Glycerol MSDS Thimerosal MSDS
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Form
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Liquid
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Concentration
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0.200 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Bcl3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Bcl3
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Bcl3 antibody - more information
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Customer reviews (feedback) regarding Bcl3 antibody |
Customer FAQs regarding Bcl3 antibody |
Protocols for Bcl3 antibody |
Price and availability of products related to Bcl3 antibody |
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Contact Abcam with a Technical Enquiry about Bcl3 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"