Anti-Beta Lactamase antibody (ab12252)

Overview

  • Product nameAnti-Beta Lactamase antibodySee all Beta Lactamase primary antibodies ...
  • Description
    Mouse monoclonal to Beta Lactamase
  • SpecificityThis antibody specifically recognizes Type IV Beta Lactamase of Enterobacter cloacae.
  • Tested applicationsELISA more details
  • Species reactivity
    Enterobacter cloacae.
  • Immunogen

    Type IV Beta Lactamase from Enterobacter cloacae.

  • General notesDilute in PBS or medium which is identical to that used in the assay system.

Properties

Applications

Our Abpromise guarantee covers the use of ab12252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA
  • Application notesELISA: Use at a concentration of 10 - 20 µg/ml. Optimized for Beta Lactamase on solid
    phase at 10 µg/ml.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThe beta lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta lactams are structurally related through the presence of a core beta lactam ring. Bacterial resistance to beta lactams continues to increase, primarily due to the production of beta lactamases. Beta lactamases catalyze the hydrolysis of the beta lactam bond, which destroys antibacterial activity. Bacteria that produce TEM type or SHV type beta lactamases have point mutations in structural genes that have extended the substrate specificity of these beta lactamases. As a result, many of the beta lactamase producing Gram negative pathogens have become multidrug resistant.
    • Alternative names
      • AmpA antibody
      • AmpC antibody
      • Cephalosporinase antibody

    References for Anti-Beta Lactamase antibody (ab12252)

    ab12252 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry.

    ab12251 and ab12252 were derived from mice that were immunized with the full-length beta lactamse. The immunogen of ab12251 was recombinant TEM-1 beta-lactamase while ab12252 was native Type IV beta-lactamase from ...

    Read More

    Thank you for contacting us. The lactamases appear to be well-conserved, and the antibodies ab97678 and ab12251 are likely to react with a variety of them. They may possibly recognize your sequence but the epitopes they recognize have not been mappe...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"