You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameBik peptideSee all Bik proteins and peptides ...
  • Protein descriptionSynthetic peptide - N-terminus of Human Bik. This peptide was used as an immunogen for ab41716 - Bik antibody.

    • Properties

  • Purification notes75% pure peptide.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab41909 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Blocking
  • Application notesBL: Use at an assay dependent dilution. This peptide is used for blocking the antibody activity of BIK (ab41716). It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37 degrees C.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        Apoptosis inducer NBKBBC1Bcl-2-interacting killer
        BCL2 interacting killerbhikhariBIKBik-like killer proteinBIK_HUMANBIP 1BIP1BP 4BP4cb 60NBK
      see all
  • FunctionAccelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
  • DomainIntact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
  • Cellular localizationEndomembrane system. Around the nuclear envelope, and in cytoplasmic membranes.

    • Target information above from: UniProt accession Q13323 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Bik peptide (ab41909)

    ab41909 has not yet been referenced specifically in any publications.

    Publishing research using ab41909 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab41909 Submit a Question for ab41909

    There are currently no Abreviews or Questions for ab41909.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"