Anti-Biliverdin Reductase antibody (ab54877)

Overview

• Product nameAnti-Biliverdin Reductase antibodySee all Biliverdin Reductase primary antibodies ...
• Description
  Mouse monoclonal to Biliverdin Reductase
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length protein, corresponding to amino acids 1-297 of Human Biliverdin Reductase

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  PBS, pH 7.2
• Concentration information loading...
• PurityProtein G purified
• Clonality Monoclonal
• IsotypeIgG2a
• Light chain typekappa
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Oxidative stress

  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • MAPK Pathway

  • Cell Biology
  • Other Antibodies
  • Oxidative Stress

Applications

Target

• RelevanceBiliverdin Reductase (BVR) catalyzes the final step in the heme metabolic pathway, the reduction of biliverdin IX{alpha} to bilirubin, with the concomitant oxidation of a NADH or NADPH cofactor. The enzyme remains unique among all biological catalysts described to date in having a dual pH/cofactor-dependent activity profile. Human biliverdin reductase (hBVR) has been recently shown to be a Ser/Thr/Tyr kinase in the MAPK insulin/insulin-like growth factor 1 (IGF1)-signaling cascade. BVR together with its substrate, biliverdin, and product, bilirubin, have recently been revealed to be important players in cellular signal transduction pathways, gene expression and oxidative response. These features make BVR unusually interesting and unique among all enzymes characterized to date.
• Cellular localizationCytoplasmic
• Database links
  • Entrez Gene: 644 Human
  • Omim: 109750 Human
  • SwissProt: P53004 Human
  • Unigene: 488143 Human

• Alternative names
  Biliverdin IX alpha reductase antibodyBiliverdin reductase A antibodyBLVR A antibody

  BLVR antibodyBLVRA antibodyBVR A antibodyBVR antibodyBVRA antibodyZinc metalloprotein antibody

  see all

Anti-Biliverdin Reductase antibody images

• 

  Western blot - Anti-Biliverdin Reductase antibody (ab54877)
  
  
  Predicted band size : 33 kDa