Anti-Bim antibody, prediluted (ab15185)
- Product nameAnti-Bim antibody, predilutedSee all Bim primary antibodies ...
- DescriptionRabbit polyclonal to Bim, prediluted
- Tested applicationsIHC-P more details
- Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
Synthetic peptide (Human) (N terminal).
- Positive controlHeLa cells, Placenta
- Storage instructionsStore at +4°C.
- Storage bufferPreservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6
- Concentration information loading...
- Clonality Polyclonal
Our Abpromise guarantee covers the use of ab15185 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- FunctionInduces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
- Tissue specificityIsoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.
- Sequence similaritiesBelongs to the Bcl-2 family.
- DomainThe BH3 motif is required for Bcl-2 binding and cytotoxicity.
- Cellular localizationMitochondrion and Endomembrane system. Associated with intracytoplasmic membranes.
- BCL2 like 11 antibodyApoptosis facilitator antibodyB2L11_HUMAN antibody
- BAM antibodyBcl 2 interacting mediator of cell death antibodyBcl 2 interacting protein Bim antibodyBcl 2 like protein 11 antibodyBcl 2 related ovarian death agonis antibodyBcl 2 related ovarian death agonist antibodyBcl-2-like protein 11 antibodyBCL2 interacting mediator of cell death antibodyBCL2 interacting protein Bim antibodyBCL2 like 11 (apoptosis facilitator) antibodyBCL2 like 11 antibodyBCL2 like 11 apoptosis facilitator antibodyBCL2 like protein 11 antibodyBCL2 related ovarian death agonist antibodyBcl2-interacting mediator of cell death antibodyBcl2-L-11 antibodyBCL2L11 antibodyBIM alpha3 antibodyBIM alpha4 antibodyBIM alpha5 antibodyBIM alpha6 antibodyBIM antibodyBIM beta6 antibodyBIM beta7 antibodyBimEL antibodyBimL antibodyBOD antibody
References for Anti-Bim antibody, prediluted (ab15185)
ab15185 has not yet been referenced specifically in any publications.