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Anti-Blood Group B Antigen antibody [HEB-29] (ab2524)

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Overview

Product name

Anti-Blood Group B Antigen antibody [HEB-29]
See all Blood Group B Antigen products (3) ...

Description

Mouse monoclonal [HEB-29] to Blood Group B Antigen

Specificity

This antibody recognizes human blood group B antigens. The specifity of the antibody HEB-29 was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood.

Tested applications

Agglutination, IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Mixture of erythrocytes of blood group B and glycoprotein fraction isolated from the saliva of secretors with blood group B.

Properties

Form

Liquid

Storage instructions

Store at +4°C. Do not freeze.

Storage buffer

Preservative: None
Constituents: Tissue Culture Supernatant

Purity

Tissue culture supernatant

Purification notes

Concentrated by ultrafiltration (100 kDa cut-off). Actual immunoglobulin concentration not determined.

Clonality

Monoclonal

Clone number

HEB-29

Myeloma

unknown

Isotype

IgM

Light chain type

unknown

Research areas

Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Cardiovascular >> Blood >> Blood Cell Antigens

Applications

Show applications key

Our Abpromise guarantee covers the use of ab2524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    Agglutination

     Agg: Use at an assay dep...Read more →

    Agg: Use at an assay dependent dilution. (The minimum titre is 1:128 with erythrocytes of blood group B. )

  • ShowHide

    IHC-P

     IHC-P: Use at an assay d...Read more →

    IHC-P: Use at an assay dependent dilution.

Target

Relevance

Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Database links

References for Anti-Blood Group B Antigen antibody [HEB-29] (ab2524)

This product has been referenced in:

  • Vanak Jet al. Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities. Neoplasma 36:479-88 (1989).Read more (PubMed: 2475797) »

See 1 publication for this product

Publishing research using ab2524? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"