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Anti-Blood Group B Antigen antibody [Z5H-2] (ab24224)

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Overview

Product name

Anti-Blood Group B Antigen antibody [Z5H-2]
See all Blood Group B Antigen products (3) ...

Description

Mouse monoclonal [Z5H-2] to Blood Group B Antigen

Tested applications

ICC/IF, ELISA, WB, Flow Cyt, IPmore details

Cross reactivity

Reacts with

Human

Immunogen

Antigen B of blood cells.

Properties

Form

Liquid

Storage instructions

Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Protein A purified

Purification notes

Product purified by Protein A from ascites fluid.

Clonality

Monoclonal

Clone number

Z5H-2

Isotype

IgM

Research areas

Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Cardiovascular >> Blood >> Blood Cell Antigens

Applications

Show applications key

Our Abpromise guarantee covers the use of ab24224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ICC/IF

     

  • ELISA

     

  • WB

     

  • Flow Cyt

     

  • IP

     

Application notes

ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
ICC/IF: Use at an assay dependent dilution PMID 17666368.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Database links

References for Anti-Blood Group B Antigen antibody [Z5H-2] (ab24224)

This product has been referenced in:

  • Sundin Met al. No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients. Haematologica 92:1208-15 (2007). ICC/IF; Human.Read more (PubMed: 17666368) »

See 1 publication for this product

Publishing research using ab24224? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"