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Product Name 

Blood Group H1 (O) antigen antibody [17-206]

Product type 

Primary antibodies

Description 

Mouse monoclonal [17-206] to Blood Group H1 (O) antigen

Immunogen 

SW-403 Colon Cancer Cell Line (Human).

Reacts with 
(species key)

Hu

Specificity 

Blood Group Antigen H (O) Type 1 (BG4).
This antibody not cross-react with the H blood group substance of the Type 2 backbone.

Tested applications 
(see key)

IHC-P


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-P: Use at an assay dependent dilution. Antigen retrieval is not essential but may optimise staining.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Kidney or antrum (human).

Research areas 

Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens

Relevance 

Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood Group H1 (O) is one of a series of well characterised murine monoclonal antibodies detecting blood group specificities of the ABH and Lewis systems. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

28    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

17-206

Isotype 

IgG3

Purity 

Ascites

Storage buffer 

Preservative: 0.01% Sodium Azide
Constituents: 1% BSA, 0.1M PBS

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Store at +4°C.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Blood Group H1 (O) antigen antibody [17-206] is on this datasheet. But please do contact us if you would like any reassurance!



References for Blood Group H1 (O) antigen antibody [17-206] (ab3355)

Specific publication references   This product has been used in:

Ota MS et al. Combined in silico and in vivo analyses reveal role of Hes1 in taste cell differentiation. PLoS Genet 5:e1000443 (2009). PubMed: 19343206

If you publish research using ab3355 please let us know so that we can cite the reference on this datasheet.

 

Search PubMed (MEDLINE) for references to Blood Group H1 (O) antigen

 

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