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Anti-Blood Group H1 (O) antigen antibody [17-206] (ab3355)

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Overview

Product name

Anti-Blood Group H1 (O) antigen antibody [17-206]

Description

Mouse monoclonal [17-206] to Blood Group H1 (O) antigen

Specificity

Blood Group Antigen H (O) Type 1 (BG4). This antibody not cross-react with the H blood group substance of the Type 2 backbone.

Tested applications

IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

SW-403 Colon Cancer Cell Line (Human).

Positive control

Kidney or antrum (human).

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.01% Sodium Azide
Constituents: 1% BSA, 0.1M PBS

Concentration

Concentration information loading...

Purity

Ascites

Clonality

Monoclonal

Clone number

17-206

Isotype

IgG3

Research areas

Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens
Cardiovascular >> Blood >> Blood Cell Antigens

Applications

Show applications key

Our Abpromise guarantee covers the use of ab3355 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    IHC-P

     IHC-P: Use at an assay d...Read more →

    IHC-P: Use at an assay dependent dilution. Antigen retrieval is not essential but may optimise staining.

Target

Relevance

Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood Group H1 (O) is one of a series of well characterised murine monoclonal antibodies detecting blood group specificities of the ABH and Lewis systems. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Database links

References for Anti-Blood Group H1 (O) antigen antibody [17-206] (ab3355)

This product has been referenced in:

  • Ota MSet al. Combined in silico and in vivo analyses reveal role of Hes1 in taste cell differentiation. PLoS Genet 5:e1000443 (2009).Read more (PubMed: 19343206) »

See 1 publication for this product

Publishing research using ab3355? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"