Anti-Bmi1 antibody [2704C2a] (ab54349)
- Storage instructionsStore at 4°C for up to one year. Upon use, aliquot and store at -20°C or -80°C.
- Storage bufferPreservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
- Concentration information loading...
- PurityProtein G purified
- Purification notesThis antibody was purified from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Sterile filtered through a 0.22 µm membrane.
- Clonality Monoclonal
- Clone number2704C2a
Our Abpromise guarantee covers the use of ab54349 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use at an assay dependent dilution. Predicted molecular weight: 37 kDa.|
|IHC-P||IHC-P: Use at an assay dependent dilution. PubMed: 20818389|
|Dot Blot||Dot: Use at an assay dependent dilution.|
- FunctionComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
- Sequence similaritiesContains 1 RING-type zinc finger.
modificationsMonoubiquitinated (By similarity). May be polyubiquitinated; which does not lead to proteasomal degradation.
- Cellular localizationNucleus. Cytoplasm.
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- Bmi 1 antibody
- BMI1 antibody
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- BMI1_HUMAN antibody
- Flvi 2/bmi 1 antibody
- FLVI2/BMI1 antibody
- MGC12685 antibody
- Murine leukemia viral (bmi 1) oncogene homolog antibody
- Oncogene BMI 1 antibody
- PCGF 4 antibody
- PCGF4 antibody
- Polycomb complex protein BMI 1 antibody
- Polycomb complex protein BMI-1 antibody
- Polycomb group protein Bmi1 antibody
- Polycomb group ring finger 4 antibody
- Polycomb group RING finger protein 4 antibody
- RING finger protein 51 antibody
- RNF 51 antibody
- RNF51 antibody
Anti-Bmi1 antibody [2704C2a] images
Anti-Bmi1 antibody [2704C2a] (ab54349) + immunizing recombinant protein
Predicted band size : 37 kDa