Anti-Bmi1 antibody [2704C2a] (ab54349)
- Storage instructionsStore at 4°C for up to one year. Upon use, aliquot and store at -20°C or -80°C.
- Storage bufferPreservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
- Concentration information loading...
- PurityProtein G purified
- Purification notesThis antibody was purified from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Sterile filtered through a 0.22 µm membrane.
- Clonality Monoclonal
- Clone number2704C2a
Our Abpromise guarantee covers the use of ab54349 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use at an assay dependent dilution. Predicted molecular weight: 37 kDa.|
|IHC-P||IHC-P: Use at an assay dependent dilution. PubMed: 20818389|
|Dot Blot||Dot: Use at an assay dependent dilution.|
- FunctionComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
- Sequence similaritiesContains 1 RING-type zinc finger.
modificationsMonoubiquitinated (By similarity). May be polyubiquitinated; which does not lead to proteasomal degradation.
- Cellular localizationNucleus. Cytoplasm.
- B lymphoma Mo MLV insertion region (mouse) antibodyB lymphoma Mo MLV insertion region 1 homolog antibodyBmi 1 antibody
- BMI1 antibodyBMI1 polycomb ring finger oncogene antibodyBMI1_HUMAN antibodyFlvi 2/bmi 1 antibodyFLVI2/BMI1 antibodyMGC12685 antibodyMurine leukemia viral (bmi 1) oncogene homolog antibodyOncogene BMI 1 antibodyPCGF 4 antibodyPCGF4 antibodyPolycomb complex protein BMI 1 antibodyPolycomb complex protein BMI-1 antibodyPolycomb group protein Bmi1 antibodyPolycomb group ring finger 4 antibodyPolycomb group RING finger protein 4 antibodyRING finger protein 51 antibodyRNF 51 antibodyRNF51 antibody
Anti-Bmi1 antibody [2704C2a] images
Anti-Bmi1 antibody [2704C2a] (ab54349) + immunizing recombinant protein
Predicted band size : 37 kDa