Overview

  • Product name
  • Description
    Goat polyclonal to Bonzo
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide:

    SEDNSKTFSASHN

    with a Cysteine residue linker, corresponding to C terminal amino acids 321-333 of Human Bonzo (NP_006555.1).

  • Positive control
    • Human thymus tissue; HEK293 lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 39 kDa.Can be blocked with Bonzo peptide (ab8388).
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
  • Tissue specificity
    Expressed in lymphoid tissues and activated T cells.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C X C chemokine receptor type 6 antibody
    • C-X-C chemokine receptor type 6 antibody
    • CD 186 antibody
    • CD186 antibody
    • CD186 antigen antibody
    • CDw186 antibody
    • Chemokine (C X C motif) receptor 6 antibody
    • Chemokine C X C motif receptor 6 antibody
    • Chemokine CXC motif receptor 6 antibody
    • Chemokine receptor 6 antibody
    • CXC chemokine receptor type 6 antibody
    • CXC R6 antibody
    • CXC-R6 antibody
    • CXCR 6 antibody
    • CXCR-6 antibody
    • CXCR6 antibody
    • CXCR6_HUMAN antibody
    • G protein coupled receptor antibody
    • G protein coupled receptor bonzo antibody
    • G protein coupled receptor STRL 33 antibody
    • G protein coupled receptor STRL33 antibody
    • G protein coupled receptor TYMSTR antibody
    • G-protein coupled receptor bonzo antibody
    • G-protein coupled receptor STRL33 antibody
    • STRL 33 antibody
    • STRL33 antibody
    • TYMSTR antibody
    see all

Images

  • ab125115, at 3.75µg/ml, staining Bonzo in formalin-fixed, paraffin-embedded Human thymus tissue by Immunohistochemistry.
  • Anti-Bonzo antibody (ab125115) at 1 µg/ml + HEK293 lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 39 kDa


    Exposure time : 1 hour

References

This product has been referenced in:
  • Hald SM  et al. Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. BMC Cancer 15:441 (2015). IHC . Read more (PubMed: 26021984) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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