Overview

  • Product name
  • Description
    Rabbit polyclonal to C1D
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Hamster, Cow, Orangutan
  • Immunogen

    Recombinant full length protein corresponding to Human C1D aa 1-135.
    Sequence:

    MAGEEINEDY PVEIHEYLSA FENSIGAVDE MLKTMMSVSR NELLQKLDPL EQAKVDLVSA YTLNSMFWVY LATQGVNPKE HPVKQELERI RVYMNRVKEI TDKKKAGKLD RGAASRFVKN ALWEPKSKNA SKVAN


    Database link: Q13901

  • Positive control
    • Human skin tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab211429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 15 µg/ml.
WB Use at an assay dependent concentration. Predicted molecular weight: 10 kDa.

Target

  • Function
    Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.
  • Tissue specificity
    Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon.
  • Sequence similarities
    Belongs to the C1D family.
  • Post-translational
    modifications
    Phosphorylated by PRKDC.
  • Cellular localization
    Cytoplasm. Nucleus > nucleolus. EXOSC10 is required for nucleolar localization.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110036E10Rik antibody
    • AI875855 antibody
    • C1D antibody
    • C1D DNA binding protein antibody
    • C1D_HUMAN antibody
    • hC1D antibody
    • LRP1 antibody
    • MGC12261 antibody
    • MGC14659 antibody
    • MGC188504 antibody
    • Nuclear DNA binding protein antibody
    • Nuclear nucleic acid binding protein C1D antibody
    • Nuclear nucleic acid-binding protein C1D antibody
    • rCG23324 antibody
    • RGD1560600 antibody
    • Small unique nuclear receptor corepressor antibody
    • SUNCOR antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human skin tissue labeling C1D with ab211429 at 15 µg/mL.

References

ab211429 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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