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Product Name
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C3 antibody
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See all C3 antibodies (13)...
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Product type
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Primary antibodies
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Description
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Goat polyclonal to C3
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Immunogen
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Full length protein (Mouse)
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Reacts with
(species key)
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Ms
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Tested applications
(see key)
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Ie
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Ie: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Immunology >> Innate Immunity >> Complement >> Classical Pathway
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Relevance
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The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 12266 (Mouse)
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Preadsorbed antiserum
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: Physiological. pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Solid phase adsorbed to ensure specificity.
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this C3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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References for C3 antibody (ab19187)
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This product has been used in:
Haas C et al. IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice. J Immunol 160:3713-8 (1998). PubMed: 9558072
If you publish research using ab19187 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to C3
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C3 antibody - more information
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Customer reviews (feedback) regarding C3 antibody |
Customer FAQs regarding C3 antibody |
Protocols for C3 antibody |
Price and availability of products related to C3 antibody |
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C3 antibody - related products:
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C3 antibody - other tools:
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Contact Abcam with a Technical Enquiry about C3 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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