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Product Name
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C3a / C3a des Arg antibody [2991]
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See all C3a / C3a des Arg antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [2991] to C3a / C3a des Arg
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Immunogen
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Unfortunately, this information is considered to be commercially sensitive
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Reacts with
(species key)
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Hu
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Specificity
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This antibody reacts with a neo-epitope (des-Arg) on C3a that is formed when C3 is cleaved into C3a and C3b.
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at an assay dependent dilution. Predicted molecular weight: 9 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Immunology >> Innate Immunity >> Complement >> Alternative Pathway
Immunology >> Innate Immunity >> Complement >> Classical Pathway
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Relevance
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C3a (des Arg) is formed upon cleavage of C3 into C3a and C3b. Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptable to bacteria infection.
Complement C3a is rapidly inactivated by serum carboxypeptidase N which removes the C-terminal arginine residue generating C3a (desArg).
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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2991
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Isotype
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IgG1
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this C3a / C3a des Arg antibody [2991] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to C3a / C3a des Arg
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C3a / C3a des Arg antibody [2991] - more information
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