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Product Name
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C3a / C3a des Arg antibody [4H3] - Azide free
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See all C3a / C3a des Arg antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [4H3] to C3a / C3a des Arg - Azide free
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Immunogen
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Synthetic peptide: RASHLGLA, corresponding to C terminal amino acids 740-747 of Human C3a / C3a des Arg
BLAST 'RASHLGLA' with  or 
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 8-9kDa. (full length C3 is 187 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Immunology >> Innate Immunity >> Complement >> Alternative Pathway
Immunology >> Innate Immunity >> Complement >> Classical Pathway
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Relevance
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C3a (des Arg) is formed upon cleavage of C3 into C3a and C3b. Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptable to bacteria infection.
Complement C3a is rapidly inactivated by serum carboxypeptidase N which removes the C-terminal arginine residue generating C3a (desArg).
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C3a / C3a des Arg antibody [4H3] - Azide free (ab37230) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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4H3
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Isotype
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IgG1
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
Constituents: 0.1M Phosphate buffer, 0.05M Sodium chloride, pH 7.2
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Purification notes
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The concentration of this antibody is lot specific. It is in the range of 0.9-1.1 mg/ml.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this C3a / C3a des Arg antibody [4H3] - Azide free is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to C3a / C3a des Arg
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