CA19-9 antibody [121SLE] (ab3982)

Product Name 

CA19-9 antibody [121SLE]

Product type 

Primary antibodies

Description 

Mouse monoclonal [121SLE] to CA19-9

Immunogen 

Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient.

Reacts with 
(species key)

Hu

Specificity 

The antibody recognizes Sialyl Lewis a containing glycolipids.

Tested applications 
(see key)

ELISA, IHC-P

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.
IHC-P: 1/100 (PMID 20010946).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasmic

Research areas 

Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Cancer >> Tumor biomarkers >> Tumor antigens
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated

Relevance 

Mucin glucoprotein is a sialyl Lewis^a structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis^a and/or Lewis^b blood group antigens. In normal tissues, sialyl Lewis^a antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas.

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

121SLE

Isotype 

IgM

Purity 

>95% by SDS-PAGE

Storage buffer 

Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at +4°C. Do not freeze.

See below for CA19-9 antibody [121SLE] images, references, products related to ab3982 and other tools.

CA19-9 antibody [121SLE] images:

References for CA19-9 antibody [121SLE] (ab3982)

  This product has been used in: (two most recent references)

Khler S et al. E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung. Br J Cancer 102:602-9 (2010). IHC-P; Human. PubMed: 20010946

Rye PD et al. Summary report on the ISOBM TD-6 workshop: analysis of 20 monoclonal antibodies against Sialyl Lewisa and related antigens. Montreux, Switzerland, September 19-24, 1997. Tumour Biol 19:390-420 (1998). PubMed: 9701730

See all 3 publication references for this product.


If you publish research using ab3982 please let us know so that we can cite the reference on this datasheet.

Customer reviews (feedback) regarding CA19-9 antibody [121SLE]

Customer FAQs regarding CA19-9 antibody [121SLE]

Protocols for CA19-9 antibody [121SLE]

Price and availability of products related to CA19-9 antibody [121SLE]

CA19-9 antibody [121SLE] - related products: