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Product Name
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CA19-9 antibody [241] - Azide free
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See all CA19-9 antibodies (7)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [241] to CA19-9 - Azide free
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Immunogen
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Human colorectal adenocarcinoma cell-line COLO 205.
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Reacts with
(species key)
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Hu
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Specificity
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Reacts specifically with Sialyl Lewis a containing glycolipids, without detectable reactivity with Lewis a, Lewis b or structurally related substances as determined by solid-phase binding assays against glycolipid antigens. Shows minimal cross-reactivity (<1%) with Sialyl Lacto-N-tetraosylceramide.
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Tested applications
(see key)
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IHC-Fr, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-Fr: Use at an assay dependent dilution.
IHC-P: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic
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Research areas
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Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Cancer >> Tumor biomarkers >> Tumor antigens
Tags & Cell Markers >> Cell Type Markers >> Other Cell Types
Tags & Cell Markers >> Cell Type Markers >> Epi / Endo-thelial
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
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Relevance
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Mucin glucoprotein is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas.
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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241
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Myeloma
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Sp2/0
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Isotype
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IgG1
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Purity
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Protein A purified
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Storage buffer
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Preservative: None
Constituents: 0.15M Sodium chloride
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Purification notes
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IgG >98% of total peak area (Superdex 200 gel chromatography on AktaFPLC).
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Form
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Liquid
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Concentration
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2.500 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CA19-9 antibody [241] - Azide free is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to CA19-9
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