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Product Name
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CA19-9 antibody [BC/121SLE]
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See all CA19-9 antibodies (7)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [BC/121SLE] to CA19-9
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Reacts with
(species key)
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Hu
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Specificity
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CA 19-9, a carbohydrate antigenic determinant identified as a sialylated lacto-N-fucopentose II, is related to the Lewis blood group. The CA19-9 antibody has been shown to label adenocarcinomas of the pancreas, stomach, colon and gall bladder. CA 19-9 is also expressed in primary and metastatic ovarian carcinomas.
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Immunohistochemistry: Dilute 1:50-100. Incubate for 30-60 minutes at RT.
Trypsin digestion is superior to heat retrieval methods for this antibody.
We do not recommend a heat retrieval method for CA19-9.
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Positive control
(see definition)
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Colon and ovarian cancer
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Cellular localization
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Cytoplasmic
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Research areas
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Cardiovascular >> Blood >> Blood Cell Antigens >> RBC Antigens >> Blood Group Antigens
Cancer >> Tumor biomarkers >> Tumor antigens
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
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Relevance
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Mucin glucoprotein is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas.
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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BC/121SLE
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Isotype
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IgM
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Storage buffer
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PBS pH7.3 with protein carrier and preservative
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Form
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Liquid
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CA19-9 antibody [BC/121SLE] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to CA19-9
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CA19-9 antibody [BC/121SLE] - more information
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Price and availability of products related to CA19-9 antibody [BC/121SLE] |
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