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Overview

  • Product nameAnti-CABLES2 antibody
  • Description
    Rabbit polyclonal to CABLES2
  • SpecificityDetects endogenous levels of CABLES2 protein.
  • Tested applicationsWB, ELISA, ICC/IF more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from an internal sequence of human CABLES2.

  • Positive controlA549 cells, extracts from Jurkat cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab69601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/500 - 1/1000. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).
ELISA ELISA: 1/10000.
ICC/IF ICC/IF: 1/500 - 1/1000.

Target

  • RelevanceCABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers. The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1.
  • Database links
    • Alternative names
        C20orf150 antibodyCABLES 2 antibodyCdk5 and Abl enzyme substrate 2 antibody
        Ik3 2 antibodyInteractor with CDK3 2 antibody
      see all

    Anti-CABLES2 antibody images

    • Western blot - CABLES2 antibody (ab69601)
      Western blot - CABLES2 antibody (ab69601)
      All lanes : Anti-CABLES2 antibody (ab69601) at 1/500 dilution

      Lane 1 : extracts from Jurkat cells
      Lane 2 : extracts from Jurkat cells with immunising peptide at 5 µg

      Lysates/proteins at 5 µg per lane.


      Predicted band size : 52 kDa
      Observed band size : 52 kDa
    • Immunocytochemistry/ Immunofluorescence - CABLES2 antibody (ab69601)
      Immunocytochemistry/ Immunofluorescence - CABLES2 antibody (ab69601)
      A549 cells,stained with ab69601 at 1/500 dilution, with and without the immunising peptide.

    References for Anti-CABLES2 antibody (ab69601)

    ab69601 has not yet been referenced specifically in any publications.

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