Anti-CACNB1/CAB1 antibody (ab230019)
Key features and details
- Rabbit polyclonal to CACNB1/CAB1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-CACNB1/CAB1 antibody
See all CACNB1/CAB1 primary antibodies -
Description
Rabbit polyclonal to CACNB1/CAB1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat, Cow -
Immunogen
Recombinant fragment corresponding to Human CACNB1/CAB1 aa 400 to the C-terminus.
Database link: Q02641 -
Positive control
- WB: Mouse liver lysate. IHC-P: Human brain tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab230019 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/5000. Detects a band of approximately 66 kDa (predicted molecular weight: 66 kDa).
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IHC-P |
1/20 - 1/200.
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Notes |
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WB
1/1000 - 1/5000. Detects a band of approximately 66 kDa (predicted molecular weight: 66 kDa). |
IHC-P
1/20 - 1/200. |
Target
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Function
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. -
Tissue specificity
Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle. -
Sequence similarities
Belongs to the calcium channel beta subunit family.
Contains 1 SH3 domain. -
Cellular localization
Cell membrane > sarcolemma. - Information by UniProt
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Database links
- Entrez Gene: 327703 Cow
- Entrez Gene: 782 Human
- Entrez Gene: 12295 Mouse
- Entrez Gene: 50688 Rat
- Omim: 114207 Human
- SwissProt: Q9MZL7 Cow
- SwissProt: Q02641 Human
- SwissProt: Q8R3Z5 Mouse
see all -
Alternative names
- CAB1 antibody
- CACB1_HUMAN antibody
- CACNB1 antibody
see all
Images
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Anti-CACNB1/CAB1 antibody (ab230019) at 1/1000 dilution + Mouse liver lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 66 kDa
Observed band size: 66 kDa -
Paraffin-embedded human brain tissue stained for CACNB1/CAB1 using ab230019 at 1/100 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab230019 has not yet been referenced specifically in any publications.