Anti-CALM2 antibody (ab96385)

Overview

• Product nameAnti-CALM2 antibodySee all CALM2 primary antibodies ...
• Description
  Rabbit polyclonal to CALM2
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Cow
• Immunogen

  Recombinant fragment, corresponding to a region within amino acids 1-115 of Human CALM2 (AAH03354).

• Positive controlA431 whole cell lysate

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Signal Transduction
  • Signaling Pathway
  • Calcium Signaling
  • Calcium Binding Proteins

  • Signal Transduction
  • Signaling Pathway
  • Calcium Signaling
  • Calmodulin Pathway

Applications

Target

• FunctionCalmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
• Sequence similaritiesBelongs to the calmodulin family.
  Contains 4 EF-hand domains.
• Post-translational
  modificationsUbiquitination results in a strongly decreased activity.
  Phosphorylation results in a decreased activity.
• Cellular localizationCytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.

Target information above from: UniProt accession P62158 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 326597 Cow
  • Entrez Gene: 801 Human
  • Entrez Gene: 805 Human
  • Entrez Gene: 808 Human
  • Omim: 114182 Human
  • SwissProt: P62158 Human
  • Unigene: 643483 Human
  • Unigene: 282410 Human

  • Unigene: 468442 Human
  • Unigene: 515487 Human
  • Unigene: 706125 Human
  • Unigene: 722012 Human

  see all

• Alternative names
  CALM_HUMAN antibodyCalm3 antibodyCalmodulin 2 antibody

  Calmodulin antibodyCaM antibodyCAMII antibodyPHKD antibodyPHKD2 antibody

  see all

Anti-CALM2 antibody images

• 

  Western blot - CALM2 antibody (ab96385)
  Anti-CALM2 antibody (ab96385) at 1/1000 dilution + A431 whole cell lysate at 30 µg
  
  Predicted band size : 17 kDa