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Overview

  • Product nameCALM2 proteinSee all CALM2 proteins and peptides ...
  • Protein descriptionRecombinant full length Human CALM2 (amino acids 1-149), predicted MWt kDa 16kDa. (UniProt ID = P62158).
  • Uniprot accessionP62158
  • Molecular weight16kDa
  • Protein length149 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 90 % by SDS-PAGE
  • Purification notesab116467 is purified by proprietary chromatographic techniques. Purity is greater than 90.0% as determined by RP-HPLC and SDS-PAGE analysis.
  • FormLiquid
  • Storage instructionsPlease see Notes section
  • Storage bufferpH: 7.50
    Constituent: 0.32% Tris HCl
  • Concentration information loading...
  • Additional notesStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
  • Sequence notesMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDT DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE EVDEMIREADIDGDGQVNYEEFVQMMTAK
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab116467 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    HPLC HPLC: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        CALM_HUMANCalm3Calmodulin
        Calmodulin 2CaMCAMIIPHKDPHKD2
      see all
  • FunctionCalmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
  • Sequence similaritiesBelongs to the calmodulin family.
    Contains 4 EF-hand domains.
  • Post-translational
    modifications    Ubiquitination results in a strongly decreased activity.
    Phosphorylation results in a decreased activity.
  • Cellular localizationCytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.

    • Target information above from: UniProt accession P62158 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for CALM2 protein (ab116467)

    ab116467 has not yet been referenced specifically in any publications.

    Publishing research using ab116467 ? Please let us know so that we can cite the reference in this datasheet

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