Anti-Carma 3 antibody (ab137383)
Key features and details
- Rabbit polyclonal to Carma 3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Carma 3 antibody
See all Carma 3 primary antibodies -
Description
Rabbit polyclonal to Carma 3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat -
Immunogen
Recombinant fragment within Human Carma 3 aa 341-630 (internal sequence). The exact sequence is proprietary.
Database link: Q9BWT7 -
Positive control
- 293T, H1299, MOLT4 and Raji whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137383 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 116 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 116 kDa. |
Target
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Function
Activates NF-kappa-B via BCL10 and IKK. -
Tissue specificity
Detected in adult heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidney. -
Sequence similarities
Contains 1 CARD domain. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 29775 Human
- Entrez Gene: 315120 Rat
- Omim: 607209 Human
- SwissProt: Q9BWT7 Human
- Unigene: 57973 Human
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Alternative names
- Bcl10 binding protein and activator of NFKB antibody
- BIMP1 antibody
- CAR10_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab137383 has been referenced in 3 publications.
- Israël L et al. CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo. Oncogenesis 10:32 (2021). PubMed: 33824280
- Zhu L et al. TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis. Nat Cell Biol 21:1604-1614 (2019). PubMed: 31792381
- Lin J et al. MicroRNA-181b inhibits thrombin-mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10. FASEB J 30:3216-26 (2016). PubMed: 27297585