Overview

  • Product name
    CAY10505
  • Description
    Potent PI3Kγ and casein kinase 2 inhibitor
  • Biological description
    Potent, selective inhibitor of PI3Kγ (IC50 values are 30 nM (PI3Kγ), 0.94 μM (PI3Kα) and 20 μM (PI3Kβ and PI3Kδ)). Potent casein kinase 2 inhibitor (IC50 = 20 nM). Selective over 80 other kinases. Active in vivo.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Pomel V  et al. Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma. J Med Chem 49:3857-71 (2006). Read more (PubMed: 16789742) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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