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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: 0.09% Sodium Azide
Concentration information loading...
Purity Protein G purified
Purification notes The antibody was purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 61 kDa.
1/50 - 1/100.
Function Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Tissue specificity Expressed in all adult and embryonic tissues.
Sequence similarities Contains 2 chromo domains.
Post-translational modifications Not phosphorylated. Ubiquitinated.
Cellular localization Nucleus. Unassociated with chromosomes during mitosis.
Information by UniProt
CBX 1 antibody
Anti-CBX1 / HP1 beta antibody images
Western blot - CBX1 / HP1 beta antibody (ab71635)
Anti-CBX1 / HP1 beta antibody (ab71635) at 1/100 dilution + Mouse kidney tissue lysate at 12.5 µg Predicted band size : 61 kDa Observed band size : 61 kDa Additional bands at : 25 kDa,36 kDa,45 kDa. We are unsure as to the identity of these extra bands.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CBX1 / HP1 beta antibody (ab71635)
Analysis of CBX4 expression on formalin-fixed and paraffin-embedded human hepatocarcinoma tissue using ab71635 at 1:50 dilution (peroxidase conjugation secondary antibody, AEC staining).
References for Anti-CBX1 / HP1 beta antibody (ab71635)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"