Anti-CCDC106 antibody (ab105354)
Key features and details
- Rabbit polyclonal to CCDC106
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-CCDC106 antibody -
Description
Rabbit polyclonal to CCDC106 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide, 15 amino acid, from within the region of the C-terminus of Human CCDC106 (NP_037433).
-
Positive control
- WB: Human brain tissue lysate
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab105354 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 32 kDa.
|
Notes |
---|
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 32 kDa. |
Target
-
Function
Promotes the degradation of p53/TP53 protein and inhibits its transactivity. -
Cellular localization
Nucleus. Colocalizes with p53/TP53. - Information by UniProt
-
Database links
- Entrez Gene: 29903 Human
- Omim: 613478 Human
- SwissProt: Q9BWC9 Human
- Unigene: 82482 Human
-
Alternative names
- CC106_HUMAN antibody
- Ccdc106 antibody
- Coiled-coil domain-containing protein 106 antibody
see all
Images
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (3)
ab105354 has been referenced in 3 publications.
- Zhao N et al. CCDC106 promotes the proliferation and invasion of ovarian cancer cells by suppressing p21 transcription through a p53-independent pathway. Bioengineered 13:10956-10972 (2022). PubMed: 35484984
- Zhang X et al. CCDC106 promotes non-small cell lung cancer cell proliferation. Oncotarget 8:26662-26670 (2017). PubMed: 28460455
- Wang ZS et al. MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer. Oncotarget 7:44266-44276 (2016). PubMed: 27329595