Anti-CCDC6 antibody (ab155212)
Key features and details
- Rabbit polyclonal to CCDC6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-CCDC6 antibody
See all CCDC6 primary antibodies -
Description
Rabbit polyclonal to CCDC6 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Zebrafish -
Immunogen
Recombinant fragment corresponding to a region within amino acids 1-222 of Human CCDC6. (Uniprot:Q16204)
-
Positive control
- HepG2 whole cell lysate (ab7900)
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab155212 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 53 kDa.
|
Notes |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 53 kDa. |
Target
-
Tissue specificity
Ubiquitously expressed. -
Involvement in disease
Defects in CCDC6 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene. -
Domain
The protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation. -
Cellular localization
Cytoplasm. Cytoplasm > cytoskeleton. May be a cytoskeletal protein. - Information by UniProt
-
Database links
- Entrez Gene: 8030 Human
- Entrez Gene: 76551 Mouse
- Omim: 601985 Human
- SwissProt: Q16204 Human
- SwissProt: D3YZP9 Mouse
- Unigene: 591360 Human
-
Alternative names
- CCDC 6 antibody
- CCDC6 antibody
- CCDC6_HUMAN antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab155212 has not yet been referenced specifically in any publications.