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Rabbit polyclonal to CCNDBP1 - C-terminal
Synthetic peptide, corresponding to a region within amino acids 298-360 of Human CCNDBP1 (Uniprot: O95273).
CCNDBP1 transfected 293T cells; Human endometrial tissue.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 0.75% Glycine, 1.21% Tris, 10% Glycerol
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Belongs to the CCNDBP1 family.
Expression may increase during differentiation.
Information by UniProt
CCNDBP 1 antibody
Western blot - Anti-CCNDBP1 antibody - C-terminal (ab153964)
All lanes : Anti-CCNDBP1 antibody - C-terminal (ab153964) at 1/500 dilution Lane 1 : 293T lysate, non-transfected Lane 2 : 293T lysate, transfected with CCNDBP1 Predicted band size : 40 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCNDBP1 antibody - C-terminal (ab153964)
Immunohistochemical analysis of paraffin-embedded Human endomitrial tissue labeling CCNDBP1 with ab153964 at 1/100 dilution.
has not yet been referenced specifically in any publications.
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