Anti-CCNDBP1 antibody - C-terminal (ab153964)

Overview

  • Product name
    Anti-CCNDBP1 antibody - C-terminal
    See all CCNDBP1 primary antibodies
  • Description
    Rabbit polyclonal to CCNDBP1 - C-terminal
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 298-360 of Human CCNDBP1 (Uniprot: O95273).

  • Positive control
    • CCNDBP1 transfected 293T cells; Human endometrial tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab153964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 40 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
  • Tissue specificity
    Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
  • Sequence similarities
    Belongs to the CCNDBP1 family.
  • Developmental stage
    Expression may increase during differentiation.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AU022347 antibody
    • CCDB1_HUMAN antibody
    • CCNDBP 1 antibody
    • Ccndbp1 antibody
    • Cyclin D type binding protein 1 antibody
    • Cyclin-D1-binding protein 1 antibody
    • D type cyclin interacting protein 1 antibody
    • DIP 1 antibody
    • DIP1 antibody
    • GCIP antibody
    • Grap 2 and cyclin D interacting protein antibody
    • Grap 2 cyclin D interacting protein GCIP antibody
    • Grap 2 cyclin interacting protein antibody
    • Grap2 and cyclin D interacting protein antibody
    • Grap2 and cyclin-D-interacting protein antibody
    • Grap2 cyclin D interacting protein GCIP antibody
    • Grap2 cyclin interacting protein antibody
    • HHM antibody
    • HHM protein antibody
    • Human homolog of Maid antibody
    • MAID antibody
    • MAID protein antibody
    • Maternal inhibition of differentiation antibody
    • MGC109078 antibody
    • OTTMUSP00000017037 antibody
    • RP23 263D22.2 antibody
    • SECC 8 antibody
    • SSEC 8 antibody
    • Stage specific embryonic cDNA 8 antibody
    see all

Images

  • All lanes : Anti-CCNDBP1 antibody - C-terminal (ab153964) at 1/500 dilution

    Lane 1 : 293T lysate, non-transfected
    Lane 2 : 293T lysate, transfected with CCNDBP1


    Predicted band size : 40 kDa
  • Immunohistochemical analysis of paraffin-embedded Human endomitrial tissue labeling CCNDBP1 with ab153964 at 1/100 dilution.

References

ab153964 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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